Wegovy affects digestion, appetite, hydration, and multiple organ systems. While some patients experience only mild nausea, others report severe, persistent, or permanent side effects, especially at higher doses.

This page details Wegovy side effects, including warning signs that may indicate serious injury.

Why Wegovy Causes Side Effects

Wegovy’s GLP-1 activity:

  • slows gastric emptying
  • suppresses appetite
  • alters intestinal motility
  • affects fluid balance
  • changes vascular regulation

At higher doses, these effects can overwhelm the body’s ability to adapt.

Common Wegovy Side Effects

Frequently reported effects include:

  • nausea
  • vomiting
  • diarrhea
  • constipation
  • abdominal pain
  • bloating
  • fatigue
  • dizziness

These effects often occur during dose escalation.

Severe Gastrointestinal Side Effects

Persistent Vomiting & Inability to Eat

Some users experience:

  • daily vomiting
  • inability to keep food or fluids down
  • dehydration
  • repeated ER visits

Vomiting lasting more than a few days is not normal.

Motility Disorders & Bowel Shutdown

Reported conditions include:

  • gastroparesis
  • ileus
  • severe constipation
  • generalized GI dysmotility

➡️ Related: Motility Disorders

Kidney-Related Side Effects

Prolonged GI symptoms may lead to:

  • dehydration
  • acute kidney injury
  • worsening kidney disease
  • dialysis in severe cases

➡️ Related: Dehydration and Kidney Damage

Gallbladder Side Effects

Rapid weight loss may increase the risk of:

  • gallstones
  • gallbladder attacks
  • gallbladder inflammation
  • gallbladder removal surgery

➡️ Related: Gallbladder Removal

Pancreatitis Risk

Symptoms may include:

  • severe abdominal pain
  • pain radiating to the back
  • vomiting
  • hospitalization

➡️ Related: Pancreatitis

Vision Side Effects & Blindness (NAION)

Serious vision problems reported include:

  • sudden vision loss
  • blurred or dim vision
  • loss of peripheral vision
  • NAION

NAION can cause permanent blindness.

➡️ Related:

Long-Term & Persistent Side Effects

Some Wegovy users report symptoms that:

  • continue months after stopping
  • require permanent dietary restrictions
  • interfere with work and daily life
  • cause chronic disability

➡️ Related: Permanent Injuries

When to Seek Immediate Medical Care

Get urgent help if you experience:

  • vomiting lasting more than 48–72 hours
  • inability to eat or drink
  • severe abdominal pain or swelling
  • no bowel movement for several days
  • minimal urine output
  • sudden vision changes

Wegovy Side Effects and Lawsuits

Wegovy side effects are central to GLP-1 litigation, particularly cases involving:

  • severe motility disorders
  • kidney injury
  • gallbladder surgery
  • pancreatitis
  • blindness / NAION

➡️ Wegovy lawsuits: Lawsuits

Wegovy can cause side effects ranging from mild nausea to severe, permanent, and life-altering injuries, especially at higher doses. Persistent or escalating symptoms should never be ignored.

If you experienced serious side effects after using Wegovy, medical and legal review may be appropriate.

➡️ Start your review: File a Claim